منابع مشابه
Cyclic Strain Enhances Cellular Uptake of Nanoparticles
Nanoparticles (NPs) have gained increasing interest in recent years due to their potential use as drug carrier, imaging, and diagnostic agents in pharmaceutical and biomedical applications. While many cells in vivo experience mechanical forces, little is known about the correlation of the mechanical stimulation and the internalization of NPs into cells. This paper investigates the effects of ap...
متن کاملEfficiency of cellular uptake of nanoparticles via receptor-mediated endocytosis
Anand Banerjee, Alexander Berzhkovskii, and Ralph Nossal Program in Physical Biology, Eunice Kennedy Shriver National Institute of Child Health, and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA Mathematical and Statistical Computing Laboratory, Division of Computational Bioscience, Center for Information Technology, National Institutes of Health, Bethesda, Mar...
متن کاملControlling Cellular Uptake of Nanoparticles with pH-Sensitive Polymers
The major challenge in cancer therapy is to efficiently translocate drug molecules into cancer tumors without doing any damage to healthy tissues. Since there exist pH gradients between tumor and normal tissues, pH-sensitive materials may have great potential to overcome such challenge. Here, we report one new type of pH-responsive drug delivery system where pH-sensitive polymers are introduced...
متن کاملCarbohydrate functionalization of silver nanoparticles modulates cytotoxicity and cellular uptake
BACKGROUND Increasing use of silver nanoparticles (Ag-NPs) in various products is resulting in a greater likelihood of human exposure to these materials. Nevertheless, little is still known about the influence of carbohydrates on the toxicity and cellular uptake of nanoparticles. METHODS Ag-NPs functionalized with three different monosaccharides and ethylene glycol were synthesized and charac...
متن کاملVapor phase mediated cellular uptake of sub 5 nm nanoparticles
Nanoparticles became an important and wide-used tool for cell imaging because of their unique optical properties. Although the potential of nanoparticles (NPs) in biology is promising, a number of questions concerning the safety of nanomaterials and the risk/benefit ratio of their usage are open. Here, we have shown that nanoparticles produced from silicon carbide (NPs) dispersed in colloidal s...
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ژورنال
عنوان ژورنال: Physical Review Letters
سال: 2011
ISSN: 0031-9007,1079-7114
DOI: 10.1103/physrevlett.107.098101